21^st International Conference on Gastroenterology and Hepatology December 10-10, 2021 Barcelona, Spain

Hepatology is an area of medicine that deals with the diagnosis, prevention, analysis, and treatment of infections that affect the liver, gallbladder, biliary system, and pancreas. Hepatology's future promises to eradicate Hepatitis C virus infection, however a new hurdle has emerged. In Western countries, obesity and metabolic disorders, as well as related non-alcoholic fatty liver illnesses, are displacing the hepatitis C virus as the leading cause of chronic liver disease. The understanding and treatment of childhood liver problems has dramatically improved thanks to incredible advances in molecular biology, medicines, imaging, and surgery.  Recipients might now be younger or heavier thanks to surgical breakthroughs in liver transplantation. Furthermore, most children with liver illness or who have had a liver transplant today live to be adults.

Paediatric gastroenterologists work with children from the time they are born until they reach adolescence. Children are growing and have unique treatment requirements. They aren't always able to answer therapeutic questions and aren't always willing to be patient and helpful. Pediatric gastroenterologists understand how to examine and treat children in a way that is both informal and pleasing to them. Pediatric gastroenterologists concentrate on issues unique to children, such as amplification, development, physical and mental growth, and age-related social difficulties. The majority of paediatric gastroenterology offices are planned and furnished with children in mind. Most gastrointestinal issues require a combination of medicine and dietary therapy as part of the treatment plan. The goal of paediatric gastroenterology research is to reduce baby and child mortality rates, restrict the spread of infectious disease, promote healthy lifestyles for a long, illness-free life, and assist children and adolescents with their challenges.

The study of the mind, the intestine, and their interactions with regard to the understanding and regulation of gastrointestinal motility and functional gastrointestinal issues is called neuro-gastroenterology. The second type of gastrointestinal disorder studied by neurogastroenterologists is motility problems. The oesophagus, the stomach, the small intestines, and the large intestines are the four sites that motility problems affect. Clinical readings in neurogastroenterology focus mostly on common motility diseases like as gastroesophageal reflux disease, which causes damage to the esophageal mucosa due to rising stomach acid passing through the lower esophageal sphincter.

Malignant clutters of the gastrointestinal tract (GI tract) and absorption assistant organs, which include the throat, stomach, biliary framework, pancreas, small and large digestive systems, rectum, and anus, are referred to as gastrointestinal oncology. Symptoms include difficulty swallowing or defecating, as well as unusual bleeding. Colorectal cancer is the most frequent, and the most recently studied GI cancer is pancreatic ductal adenocarcinoma, which is the most lethal due to the necessity for early diagnosis and the limited efficacy of systemic treatment.

Gastrointestinal Pathology deals with the diagnosis and treatment of diseases involving the stomach, liver, pancreas, and small and large digestive tract deviations. Gastrointestinal Pathology is a branch of surgical pathology that distinguishes between neoplasmic and non-neoplasmic diseases of the GI tract's extraorgans. Endoscopic, biopsies, and resections of the gastrointestinal and pancreatico-biliary systems provide high-quality symptomatic histology. The microorganisms that live inside the human gastrointestinal tract (GIT) dwarf the host's cells, and the traits encoded by the microorganisms that live inside the GIT dwarf those of their host.

A liver illness (also known as hepatic malady) is a disease or condition that affects the liver. Swelling of the mid-section and legs, bleeding easily, changes in the colour of your faeces and pee, and jaundice, or yellowing of the skin and eyes, are all common symptoms of liver disease. Hepatitis is divided into four types (A, B, C, and E), yet approximately two billion people have been infected with hepatitis B at some point in their lives, and over 350 million people are chronic carriers of the infection. Hepatitis B has become far less common as a result of widespread vaccinations and blood screening. Hepatitis B and C, on the other hand, are responsible for up to 80% of liver cancer cases. Gallbladder stones are a very common complication that is usually asymptomatic. A few patients develop biliary colic, an irregular and persistent severe pain in the epigastrium or right upper quadrant, and occasionally between the scapula, as a result of a gallstone obstructing the cystic channel. If the cystic conduit obstruction persists, the gallbladder becomes enflamed, and the understanding results in cholecystitis, which is a severe aggravation and disease of the gallbladder. Choledocholithiasis, in which one or more stones in the common bile duct or common hepatic duct induce biliary blockage, is one of the most prevalent causes of extrahepatic biliary obstruction.

Constipation, irritable bowel syndrome, haemorrhoids, anal fissures, perianal abscesses, anal fistulas, perianal infections, diverticular diseases, colitis, colon polyps, and cancer are all examples of gastrointestinal problems. Many of these can be avoided or reduced by leading a healthy lifestyle, adopting excellent bowel habits, and getting screened for cancer.

Functional bowel diseases, for example, are common in American societies, particularly among women. Irritable bowel syndrome (IBS) and inflammatory bowel diseases like Crohn's disease (CD) and colitis are common, and some GI illnesses can be managed with a combination of diet and medicine. Common GI symptoms

Gastrointestinal Radiology, also known as GI Imaging, is a type of real-time x-ray that uses a barium-based differentiates fabric to create images of the stomach, throat, digestive tract, and other stomach-related structures. It's safe and non-invasive, and it can be used to treat corrosive reflux, analyse pain, blood in the stool, and other side effects.

Bariatric surgery is a type of weight loss surgery that entails a variety of procedures for people who are obese. Weight loss can be achieved with a gastric band, the evacuation of a portion of the stomach (sleeve gastrectomy or biliopancreatic redirection with duodenal switch), or the resection and re-routing of the small digestive tract to a small stomach pockets (gastric bypass surgery). Bariatric surgery is a collection of procedures used on persons who have a lot of huskiness.

Endoscopic ultrasonography (EUS) or echo-endoscopic with electronic chromo endoscopy capability make modest lesions like small and flat polyps and patches of dysplastic gastrointestinal mucosa easier to visualise. They enable exact classification of polyps, which may one day allow us to resect precancerous colonic polyps as if they were precancerous, while ignoring small benign hyperplastic polyps, resulting in significant healthcare investment funds. Stomach Ultrasound is used to investigate stomach pain and determine the presence of issues in the upper stomach organs. It distinguishes between a ruptured appendix, gallstones, fiery diseases, kidney stones, and liver problems. Inside the bile and pancreatic duct, modern advanced choledochoscopes have unfathomably improved symptomatic and therapeutic capacities. Adjacent tissues and blood vessels can also be determined when Doppler imaging is used. EUS is also used to visualise the liver, gall bladder, and pancreas, which are all auxiliary organs in the digestive tract.

Until date, the liver, pancreas, oesophagus, small digestive system, and colon have been the most common gastrointestinal transplants. Because transplantation is a significant surgery, the quiet must be monitored both during and after the procedure. The difficulties usually appear after the operation, when the body begins to reject the joint or organ. Hematological or imaging tests can be used to assess any issues that may arise. Liver transplantation is a procedure that involves removing an infected or damaged liver and replacing it with a full modern solid liver or a part of the liver from a healthy donor. Individuals with severe or persistent liver failure require a liver transplant in order to survive.

Animals can also become infected with a variety of microbes that cause them to get ill. Aside from the normal bouts of veterinary gastrointestinal diseases, they also become infected with common infections that afflict humans, particularly their owners and children. The diseases that are transmitted from animals to people are known as zoonotic diseases, and they frequently result in outbreaks. Enteric zoonotic illnesses are a form of zoonotic disease that affects both animals and humans' gastrointestinal tracts. Salmonella, E. coli, and Campylobacter are some of the most common bacteria that cause stomach illnesses.

Pregnant women are more susceptible to infections, which can lead to pregnancy difficulties. In some circumstances, febrile sickness combined with acute intestinal infections might result in miscarriage or early childbirth. Although certain diseases have been linked to miscarriage, there is no concrete proof that common gastrointestinal diseases induce miscarriage or early delivery. The foetus is at great risk from both the infection and the subsequent treatment and antibiotics if the infection progresses to a severe stage. Listeriosis is one such illness that can directly injure the foetus due to the organism's intracellular lifecycle, which allows it to cross the placenta and kill the baby. E. coli, Shigellosis, Clostridium difficile, Cholera, Cryptosporidium spp., Giardia lamblia, and Entamoeba spp. are some of the illnesses that can cause serious sickness in women. Due to several anatomical, hormonal, and behavioural changes during pregnancy, pregnant women are more prone to constipation, diarrhoea, faecal incontinence, and haemorrhoids.

Probiotics are increasingly being used to treat a variety of medical disorders, including allergic diseases, bacterial diseases, renal illnesses and cancer, urinary tract infections, and the aversion of tooth caries/respiratory infections. Probiotics are used to treat a wide range of gastrointestinal problems.

Antibiotic therapy is becoming more widely used as a result of mounting evidence that it can help with both main and secondary treatment techniques for gastrointestinal disease, as well as gastrointestinal consequences like bleeding and ulceration. The use of other supplementary drugs, such as corticosteroids and anticoagulants, may exacerbate these risks.

New methods for preventing and diagnosing viral hepatitis C virus (HCV) infection are rapidly developing. The introduction of interferon monotherapy, which is based on triple treatments with pegylated interferon and ribavirin, boosts the percentage of HCV genotype-1 patients who are cured by around 70%.

The gastrointestinal tract, specifically the throat, stomach, small digestive tract, internal organ, and rectum, as well as the beautification organs of ingestion, the liver, gallbladder, and pancreas, are all included in gastrointestinal illnesses. Obstruction, irritable inside clutter, haemorrhoids, butt-centric gaps, perianal abscesses, butt-centric fistulas, perianal contaminations, diverticular diseases, colitis, colon polyps, and infection are all examples of gastrointestinal issues. Keeping up a healthy lifestyle, performing uncommon entrail inclinations, and submitting to tumour screening can prevent or limit a large number of these.

Inflammatory Bowel Disease (IBD) is an idiopathic disease characterised by a dysregulated resistant response to gut microbiota. Ulcerative colitis (UC), which is restricted to the colonic mucosa, and Crohn's disease (CD), which can affect any system of the gastrointestinal tract from the mouth to the butt, includes "skip sores," and is transmural, are the two main kinds of inflammatory bowel disease. IBD has a hereditary component, and persons with this disorder are more likely to acquire cancer.

Recent biological and medicinal breakthroughs have revealed the processes of chronic liver inflammation and resulted in the development of new treatments for a variety of liver illnesses. The goal of this issue is to describe the present state of knowledge about chronic liver inflammation and its consequences, both on a scientific and clinical level. Such data will aid in the development of better patient management regimens and may improve their prognosis.

Therapeutic & Diagnostic Gastroenterology offers a comprehensive variety of modern diagnostic and therapeutic endoscopic techniques, including diagnostic and therapeutic ERCP for pancreatic disorders (papillotomy, stone extraction, stricture dilation and stenting, lithotripsy, peroral choledochoscopy and pancreatoscopy), endoscopic ultrasonography, fine needle aspiration cytology and biopsy, and target treatment. Other modern techniques include radiofrequency ablation, cyrotherapy, and endoscopic mucosal excision for Barrett's oesophagus and early cancer. Because they are used to spread infection, certain of these diagnostic tools must be sanitised before use.

Nutrition is the study of food nutrients, supplement utilisation by the body, and the relationship between nutrition, health, and infection. The focus of nutrition has shifted to metabolism and metabolic pathways (biochemical steps) by which chemicals inside the body are altered from one structure to the next. Nutrition also focuses on how a nutritious diet can prevent or lessen diseases, illnesses, and concerns. A very low-calorie diet (VLCD) is a carefully controlled eating habit plan that comprises eating 800 calories or less every day to prevent gastrointestinal issues. Probiotics are bacteria that, when taken, provide health benefits. The term probiotic is increasingly used to refer to ingested microorganisms that have been linked to human and animal health benefits. Probiotics have a variety of benefits, including lowering gastrointestinal stress, enhancing immunological health, and easing constipation. Supplements such as dietary enzymes and single cell proteins are available.